PROCESS FOR PRODUCING DIETHYLCARBAMAZINE

DESCRIPTION: Product obtained in two steps: reaction of monomethylpiperazine with diethylcarbamoyl chloride, followed by formation of the salt with citric acid leading to final product.

MAIN ADVANTAGES: Domestic production. Few steps needed for obtaining product.

MAIN APPLICATIONS: Drug used in filariosis.

STAGE OF DEVELOPMENT: Developed and optimized on laboratory scale.

PERSONS IN CHARGE: Nubia Boechat and Benjamin Gilbert

UNIT/DEPARTMENT/DIVISION: Instituto de Tecnologia em F rmacos de Manguinhos-FARMANGUINHOS / Department of Research and Technological Development