Table of Contents
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Maximum Likelihood 1
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Maximum Likelihood 2
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Maximum Likelihood Tree Reconstruction
1
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Maximum Likelihood Tree Reconstruction
1
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Maximum Likelihood Tree Reconstruction
2
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Maximum Likelihood Tree Reconstruction
3
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Maximum Likelihood Tree Reconstruction
4
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Typical Assumptions of ML Substitution
Models
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Maximum Likelihood Models 1
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Maximum Likelihood Models 2
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A case study in phylogenetic
analysis
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A four taxon problem for Deinococcus
and Thermus (Thermus, Deinococcus, Bacillus, Aquifex)
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The Jukes and Cantor Model
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Output of JC ML analysis for
(Thermus, Deinococcus, Bacillus, Aquifex)
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16s rRNA base frequencies of
Aquifex, Bacillus, Deinococcus and Thermus
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Models can be made more parameter
rich to increase their realism 1
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A gamma distribution can be
used to model site rate heterogeneity
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Models can be made more parameter
rich to increase their realism 2
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Models can be made more parameter
rich to increase their realism 3
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The GTR model of sequence evolution
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The 16S rRNA sequences of Aquifex,
Bacillus, Deinococcus, Thermus and Thermus ruber
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Output of GTR-inv sites ML analysis
for (Deinococcus, Bacillus, Aquifex, thermus and Thermus ruber)
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Estimation of ML substitution
model parameters
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Parameter estimates using the
"tree scores" command in PAUP*
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ML Parameter Estimates over
a Parsimony Tree in PAUP*
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ML tree
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ML - Advantages
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ML - Disadvantages
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Author:
Martin
Embley
Email: tme@nhm.ac.uk
Home Page: http://www.nhm.ac.uk/zoology/home/embley.htm
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