THE W.H.O. Leishmania GENOME NETWORK

Supported by the UNDP/WORLD BANK/WHO Special Programme for Research and Training in Tropical Diseases (TDR).

Chairman of the Leishmania Genome Network
Jennie Blackwell, Department of Medicine, Level 5, Addenbrooke's Hospital, Hills Rd., Cambridge CB2 2QQ, UK. Email: jmb37@cus.cam.ac.uk

Secretary
Al Ivens, Department of Biochemistry, Imperial College, Exhibition Rd., London SW7 2AZ, UK. Email: a.ivens@ic.ac.uk
OVERVIEW
The aim of the W.H.O. Leishmania Genome Network (LGN) is to obtain a detailed high-resolution map of the reference strain Leishmania major Friedlin (MHOM/IL/81/Friedlin). This is being achieved by the application of a number of complementar y approaches: the determination of a pulsed field gel (PFG) chromosomal "karyotype", shuttle cosmid clone fingerprinting to generate overlapping contigs, sequencing and mapping of expressed sequence tags (ESTs) to PFG-separated chromosomes, and the genera tion of DNA sequence from specific chromosomes. A number of laboratories within the LGN are collaborating to generate a genome map of physical and biological/functional interest. The resources that are contributing to the map are freely available to the research community: data are lodged in the LGN database LeishDB.

Give me more information on:

  • Leishmania karyotypes

  • cosmid contig mapping

  • EST sequencing

  • genomic sequencing

  • where I can get clones, etc.

  • where I can get all the software and available data

  • the laboratories involved

  • the INDEX of all Leishmania Genome Network WWW pages

  • taxonomy of Leishmania

  • the W.H.O. Leishmaniasis WWW page

  • parasite genomes page

  • ENTREZ to RETRIEVE all Leishmania sequences

    LAST DATA UPDATE: 29 JAN 1997

    Comments and suggestions please to a.ivens@ic.ac.uk